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KMID : 0357919870210020098
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Korean Journal of Pathology
1987 Volume.21 No. 2 p.98 ~ p.101
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Postirradiation Extraskeletal Osteosartcoma (A case associated with aggressive fibromatosis)
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Abstract
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A case of postirradiation extraskeletal osteosarcoma with aggressive fibromatosis of the
overlying soft tissue of radiation field is reported in a 57 year old house wife who was
treated with operation and radiation therapy for cervix carcinoma of the uterus 23 years
ago.
The overlying aggressive fibromatosis showed characteristic radiation angiitis and
atrophic vascular changes such as hyaline degeneration and obliteration of the capillaries
which. were highly campatible with radiation changes. She also had multiple osteogenic
sarcoma in pelvic cavity, occurring in the mesentery bed.
As for the histogenesis in this case, we thought the possiblity that fibroblasts went
through a process of differentiation into osteoblasts that were responsible for bone
formation in the process of malignant change of the aggressive fibromatosis.
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KEYWORD
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